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Sepracor study compares Lunesta effectiveness among ethnic groups
By Elaine Rigoli
Tampa, Fla., June 21 - Sepracor, Inc. said a double-blind, placebo-controlled six-month trial comparing race/ethnicity with Lunesta brand eszopiclone for the treatment of insomnia showed that in 1,581 patients, Caucasians (1,195) and African-Americans (236) administered Lunesta achieved statistically significant improvements across each measurement of sleep and next-day function over the treatment period versus those patients administered a placebo.
However, among Hispanic patients (150), improvements across all sleep and next-day function parameters were not statistically significant.
The company said this could be due to the small number of patients in this cohort.
The company also announced post-hoc analysis based on a separate eight-week randomized double-blind placebo-controlled 545-patient study of Lunesta in combination with fluoxetine in the treatment of patients with insomnia and co-existing major depressive disorder.
This analysis showed that patients in the Lunesta-fluoxetine treatment group demonstrated statistically significant improvements versus the placebo-fluoxetine treatment group at weeks four and eight.
Sepracor is a research-based pharmaceutical company with corporate headquarters in Marlborough, Mass.
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