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Published on 5/4/2006 in the Prospect News Biotech Daily.

Seattle Genetics says SGN-30 showed antitumor response in phase 2 trial

By Elaine Rigoli

Tampa, Fla., May 4 - Seattle Genetics, Inc. reported data from its ongoing phase 2 clinical trial, evaluating SGN-30 in cutaneous anaplastic large cell lymphoma (ALCL) and other lymphoproliferative disorders, which showed that multiple patients achieved objective antitumor responses to SGN-30 therapy, including both complete and partial responses.

The study includes patients with relapsed or refractory CD30-expressing cutaneous T-cell disease, including cutaneous ALCL, transformed mycosis fungoides and lymphomatoid papulosis, the company said in a news release.

"We are encouraged by our data in this relapsed and refractory patient population, especially the high response rate with SGN-30 and the significant durations of response observed in several patients," president and chief executive officer Clay B. Siegall said in the release.

"SGN-30 may provide an important therapeutic option for advanced cutaneous T-cell malignancies, which are often painful, disfiguring and can greatly impact patients' quality of life."

Seattle Genetics is a biotechnology company based in Bothell, Wash.


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