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Samaritan reports positive preliminary results of 10-day HIV trial
By Elaine Rigoli
Tampa, Fla., May 30 - Samaritan Pharmaceuticals Inc. announced its preliminary results showing antiviral activity in only 10 days with its phase 2 10-day monotherapy study where SP-01A, an oral entry inhibitor, was tested "alone" in patients experiencing HIV drug resistance.
Samaritan said the double-blind, placebo controlled, multi-dose study assessed SP-01A's safety and effect on viral load in HIV-1 positive individuals, with evidence of increasing viral load, despite treatment with antiretroviral therapy.
In the preliminary finding, SP-01A was found to have a 0.4 log10 difference between the high dose group (800 mg/day) and the placebo control group.
In addition, there was a dose-dependent relationship in the number of subjects who had a reduction in viral load with the high-dose group (800 mg/day) showing the most difference as compared to a placebo (55% vs. 0%, respectively), according to a news release.
Located in Las Vegas, Samaritan develops therapeutics for AIDS, Alzheimer's, cancer and heart-disease patients.
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