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Access Pharmaceuticals begins dosing in phase 2 study of ProLindac in ovarian cancer
By Lisa Kerner
Charlotte, N.C., June 8 - Access Pharmaceuticals Inc. said it began the first company-sponsored phase 2 clinical study of ProLindac, a novel DACH platinum-polymer prodrug, in the treatment of ovarian cancer, with the dosing of the first patient in France.
The open-label trial is being conducted in Europe and managed by Cvitkovic and Associates.
"In our phase 1 trial, there were two responses in ovarian patients who had relapsed after prior cis- or carboplatin therapy," chief executive officer Rosemary Mazanet said in a company news release.
"Given these promising early results for ProLindac, we are now eager to see what the response rate will be in a larger study at a phase 2 dose."
The company said it expects interim results from the study by the end of the year and additional clinical trials in other cancers are planned.
Dallas-based Access is an emerging biopharmaceutical company specializing in propriety products for the treatment and supportive care of cancer patients.
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