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Published on 11/29/2005 in the Prospect News Biotech Daily.

ProtoKinetix study finds AAGP effective against ultraviolet-C radiation

By Angela McDaniels

Seattle, Nov. 29 - ProtoKinetix Inc. said its AAGP acted as an effective protective agent against ultraviolet-C radiation in company research.

Researchers exposed untreated adult fibroblast skin cells and cells treated with 15mg of AAGP to UV radiation. After two days, 85% of untreated skin cells were dead, compared to 10% of treated skin cells. After three days, all untreated skin cells were dead, compared to 37% of treated cells, the company said.

ProtoKinetix conducted the tests after previous results demonstrated the strong preservative effects of AAGP on skin fibroblasts treated with hydrogen peroxide to induce oxidative stress.

AAGP could have major implications for the skin product industry since it protects against both environmental stresses and UV exposure, the company said.

UV radiation is associated with aging and is one of the major causes of skin cancer. It causes a wide variety of cellular damage such as DNA damage and ionization of lipids and proteins.

ProtoKinetix is a Vancouver, B.C.-based scientific development company that develops health care products.


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