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Published on 6/12/2006 in the Prospect News Biotech Daily.

Point Therapeutics says PT-630 reduces triglycerides

By Elaine Rigoli

Tampa, Fla., June 12 - Point Therapeutics, Inc. said single-dose acute studies of PT-630 and the CP-inhibitor showed PT-630 increased insulin secretion, reduced glucose excursion and increased GLP-1 levels at similar levels to the CP-inhibitor in animals.

However, even with a single-dose administration, PT-630 demonstrated longer-term benefits in both elevation of GLP-1 levels and lowering of plasma glucose at later times than the CP-inhibitor, according to a news release.

Point Therapeutics is a Boston-based biopharmaceutical company developing a portfolio of dipeptidyl peptidase (DPP) inhibitors for use in cancer, type 2 diabetes and as vaccine adjuvants.


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