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Published on 9/14/2006 in the Prospect News Biotech Daily.

Point Therapeutics: talabostat stimulates cytokines against cancer

By Lisa Kerner

Charlotte, N.C., Sept. 14 - Point Therapeutics, Inc. said its anti-cancer agent talabostat has shown the ability to enhance the body's natural defenses against cancer (immunostimulation) by stimulating key cytokines, including IL-1 alpha.

"The very nature of talabostat's dual mechanism of action through both immunostimulation and FAP inhibition speaks to its potential versatility as a targeted agent with broad utility in several different cancers," Charles Dinarello, lead investigator, said in a company news release.

Data from a study of talabostat was presented at the American Association of Cancer Research Annual Meeting and International Conference on Molecular Diagnostics in Cancer Therapeutic Development in Chicago.

Point is a Boston-based biopharmaceutical company.


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