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Published on 12/15/2005 in the Prospect News Biotech Daily.

Pharmexa starts treatment in phase 2 trial of HER-2 Protein AutoVac with QS-21

New York, Dec. 15 - Pharmexa A/S said the first patients have begun treatment in its phase 2 trial of HER-2 Protein AutoVac in combination with the adjuvant QS-21 for breast cancer.

Participants will receive four initial immunizations over six weeks with 1.25 mg of HER-2 Protein AutoVac formulated with Alhydrogel adjuvant and mixed with QS-21 adjuvant, followed by booster immunizations every four weeks for up to 26 weeks.

The trial is being carried at 10 to 15 cancer research centers in Poland, Romania and Russia.

Each center will recruit 40 patients with active HER-2 positive breast cancer.

Pharmexa is a Hørsholm, Denmark, biotechnology company.


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