Pfizer: Exubera effective in diabetics exposed to cigarette smoke

By E. Janene Geiss

Philadelphia, Sept. 14 - Pfizer, Inc. said Thursday that new analyses show adult patients with diabetes who took Exubera (insulin human [rDNA origin]) inhalation powder were able to safely maintain good blood sugar control even if they developed a respiratory infection or were exposed to secondhand cigarette smoke.

In addition, according to a retrospective analyses of 14 Exubera phase 2 and 3 clinical studies, Exubera was well-tolerated and efficacious during respiratory illness in adults with type 1 or type 2 diabetes, the New York pharmaceutical company said in a news release.

Another new study found that while passive smoke exposure could result in decreased absorption, Exubera could be used by patients who were exposed to a smoky environment, officials said.

These analyses were presented Thursday at the annual meeting of the European Association for the Study of Diabetes in Copenhagen.

Exubera is the first inhaled form of insulin and the first insulin option in the European Union, United States, Brazil, and Mexico in more than 80 years that does not need to be administered by injection.

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