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Published on 3/13/2006 in the Prospect News Biotech Daily.

CombiMatrix, Array Genomics to expand diagnostic microarray technology

By Lisa Kerner

Erie, Pa., March 13 - Acacia Research Corp. said its CombiMatrix group's subsidiary, CombiMatrix Molecular Diagnostics (CMDX), and Paris-based Array Genomics, Inc. will co-develop, market and sell a new series of comparative genomic hybridization microarray products and services.

CMDX will manufacture the products in the United States and for distribution by Array Genomics in Europe, according to a company news release. The products, a series of arrays for the diagnosis of mental retardation anomalies, are expected to generate revenue for both companies within the next several weeks.

Array-based comparative genomic hybridization uses an ordered set of human DNA clones in a microarray format to detect unbalanced chromosome rearrangements associated with genetic maladies and syndromes.

"CMDX is positioning itself to become a leader in the burgeoning molecular diagnostics marketplace," CMDX chief executive officer Matt Watson said in the release.

"In addition to selling our [comparative genomic hybridization] products in Europe and other countries abroad, we intend to begin offering molecular diagnostic testing services at our Irvine, Calif.-based clinical laboratory."

The tests will be based on comparative genomic hybridization and gene expression profiling technologies. CMDX said it intends to file a number of its proprietary tests with the Food and Drug Administration for approval to market them within the United States.

The CombiMatrix group is developing a platform technology to produce customizable arrays to identify and determine the roles of genes, gene mutations and proteins, the release said.

Acacia, based in Newport Beach, Calif., develops, acquires and licenses patented technologies.


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