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Published on 9/15/2006 in the Prospect News Biotech Daily.

Osiris ends second quarter with $28.6 million cash, short-term investments

By Elaine Rigoli

Tampa, Fla., Sept. 15 - Osiris Therapeutics, Inc. ended its second quarter with $0.8 million in cash and $27.8 million in short-term investments - and noted it had drawn $5.0 million of the $50.0 million line of credit available for the development of Provacel under a loan agreement with Boston Scientific.

Net cash used in operating activities was $13.5 million for the six months ended June 30, primarily reflecting a net loss of $16.7 million, partially offset by $1.7 million in favorable working capital, $0.8 million in non-cash interest and stock-based compensation expense and $0.7 million in depreciation and amortization, according to a 10-Q filing with the Securities and Exchange Commission.

By comparison, net cash used for operating activities was $6.5 million for the six months ended June 30, 2005. Net cash used in operating activities for 2005 primarily reflects its net loss of $7.3 million, partially offset by $0.9 million in non-cash interest expense.

Net cash provided by investing activities was $14.3 million for the six months ended June 30 including cash flows from the sale of $15.0 million of short-term investments.

The company's long term debt included $42.3 million of convertible promissory notes due 2008. Since June 30, upon closing of its initial public offering, approximately $21.8 million of the convertible promissory notes, together with accrued interest of approximately $2.0 million, converted into shares of company common stock.

The remaining $20.6 million is a convertible promissory note issued to a foreign investor in 2005, which bears interest at a 6% per annum and has redemption premiums that start at 9% and increase over time to 27%.

The Baltimore stem-cell technology company said it may seek additional funding - prior to becoming cash-flow positive on an operational basis - through public or private financings or some combination of them. Additionally, the company said it might seek funding through collaborative arrangements if determined to be necessary or appropriate.


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