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Published on 8/28/2006 in the Prospect News Biotech Daily.

Northwest Biotherapeutics brain cancer clinical data shows increased patient survival

By Elaine Rigoli

Tampa, Fla., Aug. 28 - Northwest Biotherapeutics updated its phase 1 survival and progression data on patients from two clinical trials who have received DCVax-Brain, a therapeutic personalized cancer vaccine, which showed that:

• Seven of 16 patients are still alive, with follow-up times ranging from 18 to 75 months;

• Six of these seven patients have shown no cancer recurrence;

• In a landmark analysis at 24 months, 63% of treated patients were alive, while in historical controls 26% of patients were alive;

• 14 of 16 patients surpassed the historical control median survival of 15 months.

The company said patients from these phase 1 trials will continue to receive booster injections of DCVax-Brain over the next year.

Based in Bothell, Wash., Northwest is a biotechnology company.


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