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Published on 2/21/2006 in the Prospect News Biotech Daily.

ISTA at hold by Jefferies

ISTA Pharmaceuticals Inc. was given a hold rating by Jefferies & Co., Inc. analyst David Windley on news of positive data on two pipeline products in the past three weeks (tobra/pred and Ecabet). ISTA's near-term outlook remains tied to its three marketed products, of which only Xibrom has managed to sustain sequential growth. ISTA reported promising preliminary results from a phase 2b trial of Ecabet, an investigational treatment for dry eye. Shares of the Irvine, Calif., pharmaceutical company were down 24 cents, or 3.50%, at $6.61 on volume of 49,624 shares versus the three-month running average of 131,773 shares. (Nasdaq: ISTA)


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