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Published on 5/8/2006 in the Prospect News Biotech Daily.

Introgen's Advexin p53 used to treat Li-Fraumeni Syndrome cancer patient

By Lisa Kerner

Erie, Pa., May 8 - Introgen Therapeutics said its Advexin p53 therapy has been successfully used to treat a Li-Fraumeni Syndrome cancer patient on a compassionate use basis under a protocol authorized by the Food and Drug Administration.

The company said it will make its therapy available on a compassionate use basis to qualified Li-Fraumeni Syndrome patients with tumors refractory to standard treatment through protocols at qualifying institutions, according to a news release.

Li-Fraumeni Syndrome is an inherited genetic disorder that increases the risk of developing several types of cancer.

Advexin p53 therapy targets abnormal p53 tumor suppressor function associated with cancer initiation, progression and treatment resistance.

Introgen is an Austin, Texas, biopharmaceutical company focused on cancer therapies.


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