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Published on 7/27/2006 in the Prospect News Biotech Daily.

Amarin completes patient enrollment in Huntington's disease trial

By Elaine Rigoli

Tampa, Fla., July 27 - Amarin Corp. plc said it completed enrollment of the 240 patients targeted for its European phase 3 clinical trial of Miraxion to treat Huntington's disease (HD) ahead of schedule.

The study is being conducted in collaboration with Euro-HD at 27 neurology centers in Austria, Germany, Italy, Portugal, Spain and the United Kingdom.

The company said the trial is evaluating the effects of Miraxion compared with a placebo using the Total Motor Score-4 subscale of the Unified Huntington's Disease rating scale.

The company said the goal is for patients treated with Miraxion at a dose of two grams per day (one gram twice daily) for six months to demonstrate significant improvements in their motor functioning.

Amarin is a neuroscience company located in London.


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