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Published on 3/17/2006 in the Prospect News Biotech Daily.

Study demonstrates CardioDynamics' BioZ changes patient treatment 39% of time

By Lisa Kerner

Erie, Pa., March 17 - CardioDynamics published results of its ED-Impact trial, demonstrating that information from its BioZ ICG (impedance cardiography technology) device resulted in a change in treatment 39% of the time and a change in emergency department diagnosis 13% of the time in patients presenting with shortness of breath.

The results were published online in Academic Emergency Medicine and will be published in the print version of the journal in April, according to a company news release.

The trial enrolled 89 patients at the Cleveland Clinic and the University of Mississippi in Jackson. Of the 89 patients, 48% had congestive heart failure and 22% had chronic obstructive pulmonary disease.

A medical history, physical exam, diagnosis and treatment plan were completed for each patient by the emergency department physician and then compared to BioZ data. Any resulting changes in diagnosis and treatment plan were then noted, leading to the 13% change in diagnosis and 39% change in treatment.

A study published in Circulation noted that pulse oximetry, in comparison, changed therapy in less than 9% of emergency department patients, the release stated.

"Given the high morbidity and mortality rates and high cost of re-admissions, it is essential that emergency departments examine new strategies for treatment of older patients with shortness of breath," vice-chair of research in the Emergency Department at the Cleveland Clinic and principle investigator of the trial Dr. Frank Peacock said in the release.

CardioDynamics develops, manufactures and markets noninvasive ICG products and medical device electrodes.


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