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Published on 4/24/2006 in the Prospect News Biotech Daily.

Cytori reports benefit of adipose stem and regenerative cells in reconstructive surgery

By Lisa Kerner

Erie, Pa., April 24 - Cytori Therapeutics, Inc. said a preclinical study showed that adipose stem and regenerative cells, when administered in combination with a fat graft, improved survival of the transplanted tissue.

The results were presented at the 2006 American Society for Aesthetic Plastic Surgery Meeting in Orlando, Fla.

"This study suggests that adipose stem and regenerative cells improve the long-term viability of soft tissue transfer, which holds promising implications for breast reconstruction, cosmetic surgery and repair of congenital defects," president Marc H. Hedrick said in a company news release.

"Our findings show that the vascularization imparted by a stem cell supplement is likely a major contributor to increased tissue survival and volume retention."

In the reported study, fat tissue transfers were performed in three groups of 10 animals, with follow up at one, three and six months.

Half of the animals in each group were injected with a supplement of adipose stem and regenerative cells, with no differences in weight or morphology observed at one and three months.

A three-fold weight retention was observed after six months in the grafts injected with adipose stem and regenerative cells, the company said.

Cytori, based in San Diego, develops cell-based therapeutics using adult stem and regenerative cells derived from adipose tissue.


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